Comparison of the Algan Hemostatic Agent with Floseal in Rat Liver Laceration Bleeding Model

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dc.authoridKUMANDAS, ALI/0000-0002-7679-2126
dc.authoridEkici, Husamettin/0000-0001-6403-737X
dc.contributor.authorBinnetoglu, Kenan
dc.contributor.authorKumandas, Ali
dc.contributor.authorEkici, Husamettin
dc.contributor.authorOzbaykus, Abdullah Canberk
dc.date.accessioned2025-01-21T16:34:50Z
dc.date.available2025-01-21T16:34:50Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: Major vascular injury is one of the most important causes of death after trauma. 'The effective and speedy control of the hemorrhage is crucial in reducing deaths. Many products are used for this purpose. Today, however, an ideal product has not yet been produced and there is a strong demand for such effective hemostatic products. The aim of this study is to compare the efficacy of Algan hemostatic agent with Floseal in the liver laceration model in rats. Materials and Methods: A total of 28 rats were used in the study. Rats were divided into 4 groups, each consisting of 7 rats. Experimental liver laceration was established. In the control group. saline-impregnated gauze was applied. Algan hemostatic agent-impregnated sponge, Algan hemostatic agent powder, and Floseal gel were applied to the experimental groups. Results: There was no difference in bleeding control among the Algan hemostatic agent powder. Algan hemostatic agent-impregnated sponge, and Floseal. When compared to the control group, Algan hemostatic agent powder, Algan hemostatic agent-impregnated sponge, and Floseal were found to be very effective in bleeding control, respectively (P = .001, .012, and .002), in the experimental groups. Conclusion: This study showed that the properties of both Algan hemostatic agent powder and Algan hemostatic agent-impregnated sponge for controlling bleeding are similar to Floseal. Considering other characteristics such as Algan hemostatic agent's naturalness, easy applicability, and low cost, Algan hemostatic agent has been a promising effective hemostatic agent.
dc.description.sponsorshipThe Algan Group Health Services (Algan Group Health Services Import and Export Industry and Trade Limited Company, Istanbul, Turkey)
dc.description.sponsorshipThis study was sponsored by The Algan Group Health Services (Algan Group Health Services Import and Export Industry and Trade Limited Company, Istanbul, Turkey). The company provided the study materials for the researchers but bore no role in study design, data collection, and analysis, decision to publish, or preparation of the manuscript. The responsibility for the content of this publication lies solely with the authors and does not necessarily represent the official views of the Algan Group Health Services.
dc.identifier.doi10.5152/eurasianjmed.2022.21004
dc.identifier.endpage40
dc.identifier.issn1308-8742
dc.identifier.issue1
dc.identifier.pmid35307626
dc.identifier.scopus2-s2.0-85125856478
dc.identifier.scopusqualityQ2
dc.identifier.startpage36
dc.identifier.trdizinid524255
dc.identifier.urihttps://doi.org/10.5152/eurasianjmed.2022.21004
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay524255
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24004
dc.identifier.volume54
dc.identifier.wosWOS:000776956600007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAves
dc.relation.ispartofEurasian Journal of Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectLiver laceration; bleeding; Algan hemostatic agent; Floseal; rat
dc.titleComparison of the Algan Hemostatic Agent with Floseal in Rat Liver Laceration Bleeding Model
dc.typeArticle

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